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TNF-Alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [Plasma Membrane] - Ontify

TNF-Alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [Plasma Membrane]

Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-5357756).

Statements about TNF-Alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [Plasma Membrane]

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Instance Of

Protein Complex

Has Part(s)

BIRC2,3,4 [Cytosol]

TNF-Alpha Trimer:TNF-R1 Trimer [Plasma Membrane]

TNFRSF1A Associated via Death Domain

TNF Receptor Associated Factor 2

K63polyUb-RIPK1 [Cytosol]

Exact Match

https://identifiers.org/reactome:R-H ...

Part Of

10 items

CLIP3 and CYLD Bind TNF Signaling Complex

TNF-Alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4:TAX1BP1:TNFAIP3 [Plasma Membrane]

TNF:TNFR1:TRADD:TRAF2:RIPK1 Binds LUBAC

TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [Plasma Membrane]

TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:BIRC2/3:TAB1:TAK1:TAB2/3 [Plasma Membrane]

TAX1BP1:TNFAIP3(A20) Binds RIPK1-Containing Complexes

BIRC(cIAP1/2) Ubiquitinates RIPK1

RIPK1 Is Deubiquitinated

CYLD:CLIP3:TNF:TNFR1:TRADD:K63pUb-RIP1:TRAF2:BIRC2/3 [Plasma Membrane]

TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3 Recruits TAK1 Complex

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