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IL10 Dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [Plasma Membrane]

Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-6784755).

Statements about IL10 Dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [Plasma Membrane]

Instance Of

Protein Complex

Has Part(s)

Exact Match

https://identifiers.org/reactome:R-H ...

Part Of

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IL10 Dimer:2xp-Y-IL10RA:p-Y-JAK1 [Plasma Membrane]
Unnamed
: 1
P-Y-JAK1,p-Y-TYK2 Phosphorylate IL10RA
IL10 Dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 Binds STAT3
IL10RB:p-Y-TYK2 [Plasma Membrane]
Unnamed
: 2
IL10 Dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [Plasma Membrane]
P-Y705-STAT3 Dissociates From IL10 Dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3
IL10 Dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [Plasma Membrane]