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IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 Dimer:TOLLIP [Plasma Membrane] - Ontify
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IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 Dimer:TOLLIP [Plasma Membrane]
Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-446643).
Statements about
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 Dimer:TOLLIP [Plasma Membrane]
Instance Of
Protein Complex
Has Part(s)
IL1R1:IL1:IL1RAP [Plasma Membrane]
Toll Interacting Protein
MYD88 Dimer [Cytosol]
P-T342,T345,S346-IRAK4 [Cytosol]
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
IRAK1 Binds to MYD88 Within the IL1R Complex
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 Dimer:TOLLIP:IRAK1 [Plasma Membrane]
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 Dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [Plasma Membrane]
IRAK2 Is Phosphorylated Downstream of IRAK4 Following IL1 Receptor Activation
IRAK4 Is Activated by Autophosphorylation
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 Dimer:TOLLIP:p-S376,T378-IRAK1 [Plasma Membrane]
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