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Activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKi [Endosome Membrane]

Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-9013982).

Statements about Activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKi [Endosome Membrane]

Instance Of

Protein Complex

Has Part(s)

Activated TBK1/IKK Epsilon [Cytosol]
Unnamed
: 2
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [Endosome Membrane]
Unnamed
: 1

Exact Match

https://identifiers.org/reactome:R-H ...

Part Of

Phosphorylation of IRF-3/IRF7 and Their Release From the Activated TLR3 Complex
Recruitment of TBK1/IKK Epsilon to K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR3 Followed by Their Phosphorylation
Activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKE:IRF3/IRF7 [Endosome Membrane]
IRF3/IRF7 Recruitment to P-TBK1/P-IKK Epsilon Bound to the Activated TLR3
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