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P-S177,S181-IKKB:IKKA:NEMO [Cytosol] - Ontify
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P-S177,S181-IKKB:IKKA:NEMO [Cytosol]
Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-202513).
Statements about
P-S177,S181-IKKB:IKKA:NEMO [Cytosol]
Instance Of
Protein Complex
Has Part(s)
Component of Inhibitor of Nuclear Factor Kappa B Kinase Complex
Inhibitor of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma
P-S177,S181-IKBKB [Cytosol]
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
10 items
Ubiquitination of NEMO by TRAF6
Phosphorylation of IKK-Beta by TAK1
Activation of IKK Complex
K63polyUb-P-3T,1S-TAK1 Phosphorylates IKK-Beta
IKBKB Phosphorylates NFkB P105 Within the NFkB P105:TPL2:ABIN2 Complex
NFKBIA Variant Is Not Phosphorylated Within IkBA:NF-kappaB
IKBKB Phosphorylates TPL2 (MAP3K8) at Ser400
Active IKBKB Phosphorylates NF-Kappa-B Inhibitor
Activated TAK1 Mediates Phosphorylation of the IKK Complex
Ubiquitination of IKBKG by TRAF6
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