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Activated Thrombin (Factor IIa) [Extracellular Region]
Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-156786).
Statements about
Activated Thrombin (Factor IIa) [Extracellular Region]
Instance Of
Protein Complex
Has Part(s)
Coagulation Factor II, Thrombin
Unnamed
:
1
Calcium(2+)
Unnamed
:
6
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
27 items
Factor XI:platelet Glycoprotein (GP) Ib:IX:V Complex -> Factor XIa:platelet Glycoprotein (GP) Ib:IX:V Complex (Thrombin Catalyst)
GP1b-IX-V Complex:activated Thrombin (Factor IIa) [Plasma Membrane]
Thrombin:Proteinase-Activated Receptors [Plasma Membrane]
Factor IIa Inhibitors (Compounds) Binds IIa
Factor VIII:von Willibrand Factor Multimer -> Factor VIIIa + Factor VIIIa B A3 Acidic Polypeptide + Von Willibrand Factor Multimer
Activated Thrombin (Factor IIa) Cleaves PAR3,4, Activating Them
Factor IIa Inhibitors (Peptide) Binds IIa
Factor IIa Inhibitors (Peptide):IIa [Extracellular Region]
Activated Thrombin (Factor IIa) + Antithrombin III:heparin -> Thrombin:antithrombin III:heparin
Activated Thrombin (Factor IIa):SERPIND1 [Extracellular Region]
Thrombin:cleaved SERPINC1 [Extracellular Region]
Factor XIII -> Factor XIII Cleaved Tetramer + 2 Factor XIII A Activation Peptides
Cleavage of Factor XII Variant by Activated Thrombin
Activated Thrombin (Factor IIa) + Thrombomodulin -> Activated Thrombin:thrombomodulin
Factor V -> Factor Va + Factor V Activation Peptide
Proteinase-Activated Receptors Can Bind Thrombin
Factor IIa Inhibitors (Compounds):IIa [Extracellular Region]
Heparin Cofactor 2 (SERPIND1) Binds Activated Thrombin (Factor IIa)
Thrombin Proteolyzes IGF:IGFBP3:ALS
F8 Variant Is Not Cleaved by Thrombin
Prothrombin -> Activated Thrombin (Factor IIa) + Thrombin Activation Peptide (Xa Catalyst)
Ligands of GPCRs that Activate Gq/11 [Extracellular Region]
Thrombin Binding to GP1b:IX:V
Prothrombin -> Activated Thrombin (Factor IIa) + Thrombin Activation Peptide (Prothrombinase Catalyst)
Fibrinogen -> Fibrin Monomer + 2 Fibrinopeptide A + 2 Fibrinopeptide B
Activated Thrombin, (ELANE) [Extracellular Region]
Activated Thrombin (Factor IIa) Cleaves F2R (PAR1), Activating It
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