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P-MRN [Nucleoplasm] - Ontify
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P-MRN [Nucleoplasm]
Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-5682166).
Statements about
P-MRN [Nucleoplasm]
Instance Of
Protein Complex
Has Part(s)
MRE11 Homolog, Double Strand Break Repair Nuclease
RAD50 Double Strand Break Repair Protein
P-S343-NBN [Nucleoplasm]
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
15 items
3' Short Overhanging ssDNA-DSBs:p-MRN [Nucleoplasm]
ERCC1:XPF Cleaves Flaps Generated by SSA
3' Overhanging ssDNA-DSBs:p-MRN [Nucleoplasm]
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
Resolution of D-Loops Cleaved by MUS81:EME1 or MUS81:EME2
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
DNA DSB with Annealed 3' SsDNA Overhangs and Displaced Flaps:p-MRN [Nucleoplasm]
BLM Mediates Dissolution of Double Holliday Junction
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
DNA DSBs:p-MRN [Nucleoplasm]
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
Resolution of Holliday Junctions Cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)
Association of Ku Heterodimer with Ends of DNA Double-Strand Break
D-Loop Dissociation and Strand Annealing
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