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Assembly of Active LPL and LIPC Lipase Complexes - Ontify

Assembly of Active LPL and LIPC Lipase Complexes

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-8963889).

Statements about Assembly of Active LPL and LIPC Lipase Complexes

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Instance Of

Biological Pathway

Regulation of Lipoprotein Lipase Activity

Part Of

Plasma Lipoprotein Remodeling

Has Part(s)

12 items

HSPG Binds LPL Dimer

GPIHBP1 Binds HSPG:LPL Dimer

ANGPTL8 Binds ANGPTL3

PCSK6,FURIN Mediate Dissociation of 2 X LPL From GPIHBP1:HSPG:LPL Dimer

PCSK5 Mediates Dissociation of 2 X LPL From GPIHBP1:HSPG:LPL Dimer

MBTPS1,2 Cleaves CREB3L3 to CREB3L3(1-?) and CREB3L3(?-461)

CREB3L3 (1-?) Translocates From Cytosol to Nucleoplasm

APOA4,APOA5,APOC2,CIDEC,FGF21 Genes Express APOA4,APOA5,APOC2,CIDEC,FGF21 Proteins

LMF1,2 Bind LIPC Dimer

LMF1,2 Transport LIPC Dimer From ER Lumen to Extracellular Region

LIPC Dimer Binds Heparin

LIPC Dimer Hydrolyses TAG to DAG and FA

Exact Match

https://identifiers.org/reactome:R-H ...