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Processing of SMDT1

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-8949664).

Statements about Processing of SMDT1

Instance Of

Biological Pathway

Part Of

Has Part(s)

C2orf47:AFG3L2 Binds the Transit Peptide of SMDT1
PMPCA:PMPCB Cleaves the Transit Peptide of proSMDT1 (proEMRE)
AFG3L2 (M-AAA Protease) Degrades SMDT1 that Is Not Assembled in MCU

Exact Match

https://identifiers.org/reactome:R-H ...
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SMDT1 Assists in Assembling MCU, MCUB, MICU1, MICU2 (or MICU3) Yielding the MCU Complex
YME1L1 Proteolyzes Unassembled proSMDT1
Mitochondrial Calcium Ion Transport