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RHO GTPases Activate NADPH Oxidases - Ontify
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RHO GTPases Activate NADPH Oxidases
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5668599).
Statements about
RHO GTPases Activate NADPH Oxidases
Instance Of
Biological Pathway
Part Of
RHO GTPase Effectors
Has Part(s)
14 items
NADPH Oxidase 2 (NOX2) Complex Binds RAC1
NADPH Oxidase 2 Generates Superoxide From Oxygen
RAC2:GTP Binds NOX2 Complex
Production of Phagocyte Oxygen Radicals by NOX2 Complex Bound to RAC2:GTP
RAC1:GTP Binds NOX1 Complex
NOX1 Complex:RAC1:GTP Generates Superoxide From Oxygen
RAC1:GTP Binds NOX3 Complex
NOX3 Complex:RAC1:GTP Generates Superoxide From Oxygen
PIK3C3:PIK3R4 Phosphorylates PI to PI3P
MAPK1 or MAPK3 Phosphorylates NCF1 at Ser345
MAPK11 or MAPK14 Phosphorylates NCF1 at Ser345
PIN1 Binds P-S345-NCF1
PKC Phosphorylates NCF1
S100A8:S100A9:AA:Ca(2+) Binds NOX2 Complex
Exact Match
https://identifiers.org/reactome:R-H ...
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