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PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling - Ontify

PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-6811558).

Statements about PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling

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Instance Of

Biological Pathway

Regulation of Phosphatidylinositol 3-Kinase Signaling

Part Of

Negative Regulation of the PI3K/AKT Network

Has Part(s)

PI4P Is Phosphorylated to PI(4,5)P2 by PIP5K1A-C at the Plasma Membrane

PI5P Is Phosphorylated to PI(4,5)P2 by PIP4K2 Dimers at the Plasma Membrane

AKT1 Dephosphorylation by PP2A-B56-Beta,gamma

Inhibition of PP2A Activity by Phosphorylation of the Catalytic Subunit at Tyrosine Y307

IER3 Recruits MAPKs to PP2A-B56-Beta,gamma

MAPKs Phosphorylate PP2A

PI3K Phosphorylates PIP2 to PIP3

Exact Match

https://identifiers.org/reactome:R-H ...