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PIP3 Activates AKT Signaling - Ontify
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PIP3 Activates AKT Signaling
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-1257604).
Statements about
PIP3 Activates AKT Signaling
Instance Of
Biological Pathway
Positive Regulation of Protein Kinase B Signaling
Part Of
Intracellular Signaling by Second Messengers
Has Part(s)
13 items
AKT Phosphorylates Targets in the Cytosol
AKT Phosphorylates Targets in the Nucleus
Negative Regulation of the PI3K/AKT Network
PTEN Regulation
PIP3 Recruits PDPK1 to the Membrane
TORC2 (mTOR) Phosphorylates AKT at S473
AKT Binds PDPK1
PIP3 Recruits AKT to the Membrane
PDPK1 Phosphorylates AKT at T308
AKT Translocates to the Nucleus
PDPK1 Binds PIP2
RAC1,RAC2,RHOG Activate PI3K
PI3K Phosphorylates PIP2 to PIP3
Exact Match
https://identifiers.org/reactome:R-H ...