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Signaling by Leptin - Ontify
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Signaling by Leptin
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2586552).
Statements about
Signaling by Leptin
Instance Of
Biological Pathway
Part Of
Signal Transduction
Has Part(s)
19 items
P-STAT5 Dimerizes
STAT5 Dimers Translocate to the Nucleus
Phosphorylated STAT3 Forms Dimers
Phosphorylated STAT3 Dimer Translocates to the Nucleus
Phosphorylated STAT3 Dissociates From Leptin Receptor
Phosphorylated LEP:LEPR:JAK2:SH2B1 Binds IRS1/2
JAK2 Phosphorylates IRS in Response to Leptin
Exact Match
https://identifiers.org/reactome:R-H ...
Phosphorylated LEPR Binds SHP2 (PTPN11)
JAK2 Autophosphorylates in Response to Leptin
JAK2 Phosphorylates STAT5 in Response to Leptin
Phosphorylated LEP:LEPR:JAK2 Binds SH2B1
Leptin Binds Leptin Receptor
Phosphorylated LEPR Binds STAT3
JAK2 Phosphorylates LEPR
JAK2 Phosphoryates STAT3 in Response to Leptin
Phosphorylated LEPR Binds SOCS3
JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin
Phosphorylated STAT5 Dissociates From Leptin Receptor
Phosphorylated LEPR Binds STAT5
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