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Degradation of AXIN - Ontify
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Degradation of AXIN
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-4641257).
Statements about
Degradation of AXIN
Instance Of
Biological Pathway
Positive Regulation of Canonical Wnt Signaling Pathway
Part Of
TCF Dependent Signaling in Response to WNT
Has Part(s)
Tankyrase Binds AXIN
Tankyrase ADP-Ribosylates AXIN
RNF146 Binds RibC-AXIN:TNKS Complex
RNF146 Ubiquitinates ADP-Ribosylated AXIN
Ub-RibC-AXIN Is Degraded by the Proteasome
SMURF2 Binds AXIN
AXIN Is Ubiquitinated by SMURF2
Ubiquitinated AXIN Is Degraded by the Proteasome
Exact Match
https://identifiers.org/reactome:R-H ...