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Repression of WNT Target Genes - Ontify
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Repression of WNT Target Genes
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-4641265).
Statements about
Repression of WNT Target Genes
Instance Of
Biological Pathway
Part Of
Degradation of Beta-Catenin by the Destruction Complex
Has Part(s)
TCF/LEF Binds WNT Promoters
TLE Oligomerizes
TLE Tetramers Bind TCF/LEF at WNT Promoters
TLE Forms Non-Functional Complexes with AES
Transcription of Canonical WNT Targets Is Repressed by the TLE:HDAC and TCF/CTBP Complexes
Exact Match
https://identifiers.org/reactome:R-H ...
TCF7L2/TCF7L1 Bind CTBP1 to Repress WNT Target Genes
TLE Recruits HDAC1 to WNT Promoters