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NOTCH2 Activation and Transmission of Signal to the Nucleus - Ontify

NOTCH2 Activation and Transmission of Signal to the Nucleus

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2979096).

Statements about NOTCH2 Activation and Transmission of Signal to the Nucleus

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Instance Of

Biological Pathway

Part Of

Signaling by NOTCH2

Has Part(s)

11 items

DLL1 Binds NOTCH2

JAG1 Binds NOTCH2

JAG2 Binds NOTCH2

DLL4 Binds NOTCH2

Ubiquitination of DLL/JAG Ligands upon Binding to NOTCH2

NOTCH2-Ligand Complex Is Cleaved to Produce NEXT2

NEXT2 Is Cleaved to Produce NICD2

NICD2 Traffics to the Nucleus

NOTCH2 Binds CNTN1

Gamma-Secretase Cleaves CNTN1:NOTCH2 to Release NICD2

NOTCH2 Binds MDK

Exact Match

https://identifiers.org/reactome:R-H ...