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NOTCH1 Intracellular Domain Regulates Transcription - Ontify

NOTCH1 Intracellular Domain Regulates Transcription

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2122947).

Statements about NOTCH1 Intracellular Domain Regulates Transcription

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Instance Of

Biological Pathway

Part Of

Signaling by NOTCH1

Has Part(s)

18 items

NOTCH1 Stimulates HES1 Transcription

NOTCH1 Coactivator Complex Binds HES1 Promoter

NICD1 Displaces Co-Repressor Complex From RBPJ (CSL)

NICD1 in Complex with RBPJ (CSL) Recruits MAML

NOTCH1 Coactivator Complex Binds MYC Promoter

NOTCH1 Stimulates MYC Transcription

NOTCH1 Coactivator Complex Binds HES5 Promoter

NOTCH1 Stimulates HES5 Transcription

NOTCH1 Coactivator Complex Binds Promoters of HEY Genes

NOTCH1 Stimulates HEY Transcription

MAML in Complex with NICD1 Recruits CDK8

NICD1 Is Phosphorylated by CDK8

Phosphorylated NICD1 Binds FBXW7

Ubiquitination of NICD1 by FBWX7

NICD1 Binds HIF1A

NBEA Translocates to the Nucleus

NBEA Binds NICD1

Exact Match

https://identifiers.org/reactome:R-H ...