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EGFR Transactivation by Gastrin - Ontify
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EGFR Transactivation by Gastrin
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2179392).
Statements about
EGFR Transactivation by Gastrin
Instance Of
Biological Pathway
Part Of
Gastrin-CREB Signalling Pathway via PKC and MAPK
Has Part(s)
Diacylgycerol Activates Protein Kinase C, Alpha Type
Activated PKC-Alpha Activate MMP3
Active MMP3 Can Cleave Pro-HBEGF to Form Active HBEGF
Mature HBEGF Binds to EGFR, Triggering Dimerisation and Autophosphorylation of the Receptor
GRB2:SOS1 Binds to HBEGF:p-Y-EGFR
SOS1-Mediated Nucleotide Exchange of RAS (HB-EFG-Initiated)
Exact Match
https://identifiers.org/reactome:R-H ...
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