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G Alpha (S) Signalling Events - Ontify
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G Alpha (S) Signalling Events
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-418555).
Statements about
G Alpha (S) Signalling Events
Instance Of
Biological Pathway
Part Of
GPCR Downstream Signalling
Has Part(s)
21 items
G Alpha (S) Activates Adenylate Cyclase
Liganded Gs-Activating GPCRs Bind Inactive Heterotrimeric Gs
Liganded Gs-Activating GPCR Acts as a GEF for Gs
The Ligand:GPCR:Gs Complex Dissociates
Adenylate Cyclase Converts ATP to 3',5'-Cyclic AMP (cAMP) and Pyrophosphate
G Alpha (S) Auto-Inactivates by Hydrolysing GTP to GDP
G Protein Alpha (S):GTP Binds SRC
G Alpha (S):GTP:SRC Catalyzes SRC to P-Y416-SRC
G Alpha (S):GTP:SRC Dissociates
GPER1 Signaling
Exact Match
https://identifiers.org/reactome:R-H ...
ADRB2:Catecholamine Binds ARRB1, ARRB2
CAMP Degradation by Phosphodiesterases
ADRB2 in ADRB2:GRK Complex Is Phosphorylated
Inactive G Alpha (S) Reassociates with G Beta:gamma
PDE3A Inhibitors Bind PDE3A
PDE3A Hydrolyses cAMP to AMP
PDE3B Hydrolyses cAMP to AMP
PDE4A Hydrolyses cAMP to AMP
ADRB2:GRK Complex Dissociates to Phosphorylated ADRB2
PDE4A Binds PDE4A Inhibitors
GRKs Bind ADRB2:Catecholamine
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