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VEGFR2 Mediated Cell Proliferation - Ontify

VEGFR2 Mediated Cell Proliferation

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5218921).

Statements about VEGFR2 Mediated Cell Proliferation

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Instance Of

Biological Pathway

Has Part(s)

12 items

Calcium Binds Calmodulin

IP3 Binds to the IP3 Receptor, Opening the Endoplasmic Reticulum Ca2+ Channel

IP3R:I(1,4,5)P3 Tetramer Transports Ca2+ From ER Lumen to Cytosol

Active PLCG1 Hydrolyses PIP2

PLCG1 Disassociates From VEGFR2 and Translocate to PM

PDK1 Phosphorylates PKC

PKC Autophosphorylates

Part Of

VEGFA-VEGFR2 Pathway

Exact Match

https://identifiers.org/reactome:R-H ...

P-SPHK1 Phosphorylates Sphingosine to Sphingosine 1-Phosphate

P-6Y-VEGFR2 Binds PLCG1

DAG and Ca+2 Bind to PKC and Tether It to Membrane

SFKs Phosphorylate PLCG1

PKC Phosphorylates Sphingosine Kinase 1