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Signaling by PDGF - Ontify
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Signaling by PDGF
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-186797).
Statements about
Signaling by PDGF
Instance Of
Biological Pathway
Part Of
Signaling by Receptor Tyrosine Kinases
Has Part(s)
16 items
Downstream Signal Transduction
Translocation of PDGF From ER to Golgi
PDGF-AA Clevage by Furin
PDGF-BB Clevage by Furin
PDGF-AB Clevage by Furin
Release of Novel PDGFs as Latent Factors
Extracellular Processing of Novel PDGFs
PDGF Binds to Extracellular Matrix Proteins
PDGF Dimer Binds Two Receptors Simultaneously
Autophosphorylation of PDGF Beta Receptors
Autophosphorylation of PDGF Alpha Receptors
Autophosphorylation of PDGF Alpha/Beta Receptors
PTPN12 Dephosphorylates PDGFRB at Y1021
Olaratumab Binds PDGFRA
PDGFRs Bind Type I TKI
PDGFRs Bind Type II TKI
Exact Match
https://identifiers.org/reactome:R-H ...