Ontify

⌘S

Signal Attenuation - Ontify

Signal Attenuation

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-74749).

Statements about Signal Attenuation

Powered by

Instance Of

Biological Pathway

Part Of

Insulin Receptor Signalling Cascade

Has Part(s)

Dephosphorylation of P-Y-IRS1,p-Y-IRS2

De-Phosphorylation of P-Y427-SHC1

MAPK3,(MAPK1) Phosphorylates GRB2-1:SOS1:p-Y427-SHC1

GRB2-1:p-4S-SOS1:p-Y427-SHC1 Dissociates

MAPK3,(MAPK1) Phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2

GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 Dissociates

Binding of Grb10 to the Insulin Receptor

Exact Match

https://identifiers.org/reactome:R-H ...