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Regulated Proteolysis of P75NTR
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-193692).
Statements about
Regulated Proteolysis of P75NTR
Instance Of
Biological Pathway
Part Of
P75 NTR Receptor-Mediated Signalling
Has Part(s)
Gamma-Secretase Cleaves the P75NTR Transmembrane Domain
P75NTR ICD Signals to NF-kB
Exact Match
https://identifiers.org/reactome:R-H ...
Membrane Protein Intracellular Domain Proteolysis
Alpha-Secretase Cleaves the P75NTR Extracellular Domain
The P75NTR C-Terminal Fragment Enters Endosomes
Part of the ICD Migrates to the Nucleus
