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NRAGE Signals Death Through JNK - Ontify
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NRAGE Signals Death Through JNK
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-193648).
Statements about
NRAGE Signals Death Through JNK
Instance Of
Biological Pathway
Positive Regulation of Apoptotic Process
Part Of
Cell Death Signalling via NRAGE, NRIF and NADE
Has Part(s)
NRAGE Activates JNK
GTP-Bound RAC Contributes to JNK Activation
JNK Phosphorylates BIM, BAD and Other Targets
Active JNK Moves to the Nucleus and Phosphorylates Different Transcription Factors
Exact Match
https://identifiers.org/reactome:R-H ...
NRAGE Sequesters CHE1 in the Cytoplasm
NGF:p75NTR Complex Binds to NRAGE
P75NTR Indirectly Activates RAC and Cdc42 via a Guanyl-Nucleotide Exchange Factor