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IRE1alpha Activates Chaperones
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-381070).
Statements about
IRE1alpha Activates Chaperones
Instance Of
Biological Pathway
Part Of
Has Part(s)
Exact Match
https://identifiers.org/reactome:R-H ...
IRE1 Dimer Autophosphorylates
IRE1-Mediated Unfolded Protein Response
IRE1alpha Hydrolyzes Xbp1 mRNA and Xbp1 mRNA Is Spliced
Phosphorylated IRE1 Dimer Binds ADP
XBP1(S) Activates Chaperone Genes
IRE1 Binds IRE1 Forming Dimer
XBP(S) mRNA Is Translated and XBP1(S) Translocates to the Nucleus
Unfolded Protein Response (UPR)
IRE1:BiP Dissociates in Response to Unfolded Protein
