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Insulin Processing
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-264876).
Statements about
Insulin Processing
Instance Of
Biological Pathway
Part Of
Has Part(s)
16 items
Exact Match
https://identifiers.org/reactome:R-H ...
Oxidation of Cysteine to Cystine in Proinsulin
ZnT6 Transports Zinc Into the Golgi Apparatus
ZnT7 Transports Zinc Into the Golgi Apparatus
PCSK2 Cleaves Insulin(57-110) to Yield Insulin(90-110) and C-Peptide (Insulin(57-89))
PCSK1 Cleaves Proinsulin to Yield Insulin(25-56) and Insulin(57-110)
Cystine-Bonded Proinsulin Translocates From the Endoplasmic Reticulum to the Golgi
Proinsulin Binds Zinc and Calcium Forming Proinsulin:zinc:calcium
Proinsulin:Zinc:Calcium Complex Translocates to Immature Secretory Granule
Carboxypeptidase E Cleaves Insulin(25-56) to Yield Insulin(25-54)
SLC30A8 Transports Zn2+ From Cytosol to Secretory Granule
Insulin Processing
Peptide Hormone Metabolism
Insulin Secretory Granule Translocates Across the Cortical Actin Network
ZnT5 Transports Zinc Into Secretory Granules in Pancreatic Beta Cells
Insulin Secretory Granule Translocates to Cell Cortex
Exocyst Complex Formation
Carboxypeptidase E Cleaves C-Peptide (Insulin(57-89)) to Yield C-Peptide (Insulin(57-87))
Insulin Secretory Granule Docks at the Plasma Membrane
