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ER Quality Control Compartment (ERQC) - Ontify

ER Quality Control Compartment (ERQC)

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-901032).

Statements about ER Quality Control Compartment (ERQC)

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Instance Of

Biological Pathway

Endoplasmic Reticulum Mannose Trimming

Part Of

Calnexin/Calreticulin Cycle

Has Part(s)

MAN1B1,EDEM2 Hydrolyse 1,2-Linked Mannose (B Branch)

MAN1B1 Hydrolyses 1,2-Linked Mannose (C Branch)

MAN1B1 Hydrolyses 1,2-Linked Mannose (a Branch)

MAN1B1 Hydrolyses a Second 1,2-Linked Mannose (a Branch)

UGGT1,2 Transfers Glucose From DbGP to (Un)folded Protein:(GlcNAc)2 (Man)8b

EDEM1,3 Hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5

OS9:SEL1:ERAD E3 Ligase:DERL2 Ubiquitinates Unfolded Protein:(GlcNAc)2 (Man)9-5

Ub-Unfolded Protein:(GlcNAc)2 (Man)9-5 Translocates From ERQC to Cytosol

Glycoproteins with Lesser Folding Defects Get Transported Back to the ER and the CNX/CRT Complex

Exact Match

https://identifiers.org/reactome:R-H ...