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Tristetraprolin (TTP, ZFP36) Binds and Destabilizes mRNA - Ontify

Tristetraprolin (TTP, ZFP36) Binds and Destabilizes mRNA

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-450513).

Statements about Tristetraprolin (TTP, ZFP36) Binds and Destabilizes mRNA

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Instance Of

Biological Pathway

Regulation of mRNA Stability

Part Of

Regulation of mRNA Stability by Proteins that Bind AU-Rich Elements

Has Part(s)

ZFP36 (TTP) Recruits RNA Degradation Activities

Exact Match

https://identifiers.org/reactome:R-H ...

MK2 Phosphorylates ZFP36 (Tristetraproline, TTP)

ZFP36 (Tristetraproline, TTP) Binds AU-Rich Elements in 3' UTR of Target mRNAs

P-S60,S186-ZFP36 (Tristetraproline, TTP) Binds 14-3-3beta