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Complex I Biogenesis - Ontify
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Complex I Biogenesis
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-6799198).
Statements about
Complex I Biogenesis
Instance Of
Biological Pathway
Part Of
Respiratory Electron Transport
Has Part(s)
13 items
Exact Match
https://identifiers.org/reactome:R-H ...
NUBPL Transfers 4Fe-4S to NDUFV1, V2
Intermediate 1 Binds HP Subcomplex to Form Intermediate 2
Mitochondrial Respiratory Chain Complex I Assembly
Peripheral Arm Subunits Bind the 815kDa Complex to Form a 980kDa Complex
NDUF Subunits Bind to Form the FP Subcomplex
The 315kDa Subcomplex Binds the 370kDa Subcomplex to Form the 550kDa Complex
ND4, ND5 Bind the 550kDa Complex to Form the 815kDa Complex
COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 Bind the MCIA Complex to Form a 370kDa Subcomplex
Intermediate 2 Binds MT-ND1:NDUFAF5:NDUFAF6 to Form a 315kDa Subcomplex
NUBPL Binds 4Fe-4S
The MCIA Complex, NDUFAF2-7 All Dissociate From the 980kDa Complex, Resulting in Complex I
IP Subcomplex Binds NDUFAF3, NDUFAF4, TIMMDC1 to Form Intermediate 1
NUBPL Transfers 4Fe-4S to Complex I Subunits
NDUF Subunits Bind to Form the IP Subcomplex
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