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Glucagon-Like Peptide-1 (GLP1) Regulates Insulin Secretion - Ontify

Glucagon-Like Peptide-1 (GLP1) Regulates Insulin Secretion

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-381676).

Statements about Glucagon-Like Peptide-1 (GLP1) Regulates Insulin Secretion

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Instance Of

Biological Pathway

Regulation of Insulin Secretion

Part Of

Regulation of Insulin Secretion

Has Part(s)

12 items

GLP1R Binds GLP1

GLP1R:GLP1 Activates G(s)

Heterotrimeric G(s) Complex Dissociates

G(s):GTP Activates Adenylyl Cyclase

Activated Adenylyl Cyclase Synthesizes Cyclic AMP

PKA:AKAP79:IQGAP1 Complex Dissociates to Active PKA Subunits in Response to cAMP

Potassium Voltage-Gated Channels Close in Reponse to PKA

ER Calcium Channels Open in Response to Activated PKA

CAMP Activates EPAC1

CAMP Activates EPAC2

RAP1A Exchanges GDP for GTP

GLP1R Binds GLP1R Agonists

Exact Match

https://identifiers.org/reactome:R-H ...