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Synthesis of Ketone Bodies - Ontify

Synthesis of Ketone Bodies

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-77111).

Statements about Synthesis of Ketone Bodies

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Instance Of

Biological Pathway

Ketone Body Biosynthetic Process

Part Of

Ketone Body Metabolism

Has Part(s)

2 Acetyl-CoA <=> Acetoacetyl-CoA + CoA

Exact Match

https://identifiers.org/reactome:R-H ...

Acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH

BDH2 Dehydrogenates 3HBA

AACS Ligates CoA-SH to ACA, Forming ACA-CoA

ACSS3 Ligates CoA to CH3COO-

Acetoacetic Acid + NADH + H+ <=> Beta-Hydroxybutyrate + NAD+

HMGCLL1:Mg2+ Cleaves bHMG-CoA to Ac-CoA and ACA

HMG CoA => Acetoacetic Acid + Acetyl CoA