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Activation of Gene Expression by SREBF (SREBP) - Ontify
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Activation of Gene Expression by SREBF (SREBP)
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2426168).
Statements about
Activation of Gene Expression by SREBF (SREBP)
Instance Of
Biological Pathway
Regulation of Lipid Metabolic Process
Part Of
Regulation of Cholesterol Biosynthesis by SREBP (SREBF)
Has Part(s)
42 items
Expression of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR)
Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase)
Expression of Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS1)
SREBP1A,1C,2 Binds the TM7SF2 Promoter
SREBP1A,1C Binds the GPAM Promoter
SREBP1A,1C Binds the FASN Promoter
SREBP1A,2 Binds the LSS Promoter
SREBP1A,2 Binds the MVD Promoter
SREBP1A,2 Binds the HMGCR Promoter
SREBP1A,2 Binds the SC5DL Promoter
SREBP1A,2 Binds the CYP51A1 Promoter
SREBP1A,2 Binds the DHCR7 Promoter
SREBP1A,2 Binds the GGPS1 Promoter
SREBP1A,2 Binds the IDI1 Promoter
SREBP1A,2 Binds the MVK Promoter
SREBP1A,2 Binds the PMVK Promoter
SREBP1A,2 Binds the SQLE Promoter
SREBP1A,1C,2 Binds the FDPS Promoter
SREBP1A,1C,2 Binds the HMGCS1 Promoter
SREBP1A,1C,2 Binds the FDFT1 Promoter
Expression of 7-Dehydrocholesterol Reductase (DHCR7)
Expression of Lathosterol Oxidase (SC5D, SC5DL)
Expression of Mevalonate Kinase (MVK)
Expression of Phosphomevalonate Kinase (PMVK)
Expression of Squalene Monooxygenase (SQLE)
Exact Match
https://identifiers.org/reactome:R-H ...
SREBP1A,1C,2 Binds the ACACA Promoter
Expression of Acetyl CoA Carboxylase 1 (ACACA, ACC1)
SREBP1A,1C Binds the ACACB Promoter
Expression of Diphosphomevalonate Decarboxylase (MVD)
Expression of ELOVL6
SREBP1A,1C Binds the SCD Gene
Expression of Isopentenyl-Diphosphate Delta-Isomerase 1 (IDI1)
SREBP1A,1C,2 Binds the ELOVL6 Promoter
Expression of Geranylgeranyl Pyrophosphate Synthase (GGPS1)
Expression of Glycerol-3-Phosphate Acyltransferase (GPAM, GPAT)
Expression of Acyl-CoA Desaturase (Stearoyl CoA Desaturase, SCD)
Expression of Farnesyl Diphosphate Synthase (FDPS)
Expression of TM7SF2
Expression of Acetyl CoA Carboxylase 2 (ACACB, ACC2)
Expression of Lanosterol Synthase (LSS)
Expression of Lanosterol Demethylase (CYP51A1)
Expression of Fatty Acid Synthase (FASN)