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Beta-Oxidation of Very Long Chain Fatty Acids - Ontify

Beta-Oxidation of Very Long Chain Fatty Acids

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-390247).

Statements about Beta-Oxidation of Very Long Chain Fatty Acids

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Instance Of

Biological Pathway

Fatty Acid Beta-Oxidation Using Acyl-CoA Oxidase

Part Of

Peroxisomal Lipid Metabolism

Has Part(s)

12 items

Peroxisomal Uptake of Very Long-Chain Fatty Acyl CoA

ECI2 Isomerizes 3Z-Enoyl-CoA to 2E-Enoyl-CoA

Hexacosanoyl-CoA + O2 => Trans-2,3-Dehydrohexacosanoyl-CoA + H2O2

HSD17B4 Hydrates Trans-2,3-Dehydrohexacosanoyl-CoA

HSD17B4 Dehydrogenates 3-Hydroxyhexacosanoyl-CoA

EHHADH Hydrates Trans-2,3-Dehydrohexacosanoyl-CoA

EHHADH Dehydrogenates 3-Hydroxyhexacosanoyl-CoA

3-Ketohexacosanoyl-CoA + CoASH => Tetracosanoyl-CoA + Acetyl-CoA

Tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => Octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 Acetyl-CoA

Malonyl-CoA Is Decarboxylated to Acetyl-CoA in Peroxisome

DECR2 Reduces LCtE-CoA to T3enoyl-CoA

Peroxisomal ACOT4,6,8 Hydrolyse MCFA-CoA, LCFA-CoA

Exact Match

https://identifiers.org/reactome:R-H ...