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Synthesis of Prostaglandins (PG) and Thromboxanes (TX) - Ontify
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Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2162123).
Statements about
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Instance Of
Biological Pathway
Part Of
Arachidonic Acid Metabolism
Has Part(s)
33 items
Arachidonic Acid Is Oxidised to PGG2 by PTGS1
PGG2 Is Reduced to PGH2 by PTGS1
PGG2 Is Reduced to PGH2 by PTGS2
PTGIS, CYP8A1 Isomerise PGH2 to PGI2
TBXAS1 Isomerises PGH2 to TXA2
Exact Match
https://identifiers.org/reactome:R-H ...
PTGS2 Dimer Binds PTGS2 Inhibitors
PGH2 Is Isomerised to PGD2 by PTGDS
PGE2 Is Dehydrated to PGA2
PGH2 Is Isomerised to PGD2 by HPGDS
PGH2 Is Reduced to PGF2a by AKR1C3
15k-PGE2/F2a Is Reduced to Dhk-PGE2/F2a by PTGR1
ASA- Acetylates PTGS1
PGD2 Is Dehydrated to 15d-PGD2
PGH2 Is Reduced to PGF2a by FAM213B
Arachidonic Acid Is Oxidised to PGG2 by PTGS2
PGD2 Is Dehydrated to PGJ2
PGC2 Is Isomerised to PGB2
Prostaglandin E Synthase Isomerizes PGH2 to PGE2
PGD2 Is Reduced to 11-Epi-PGF2a by AKRIC3
Delta12-PGJ2 Is Dehydrated to 15d-PGJ2
TXB2 Is Converted to 11dh-TXB2 by TXDH
PGA2 Is Isomerised to PGC2
PGH2 Is Isomerised to PGE2 by PTGES
PGI2 Is Hydrolysed to 6k-PGF1a
TXA2 Is Hydrolysed to TXB2
PGD2/E2/F2a Is Oxidised to 15k-PGD2/E2/F2a by HPGD
PGA2 Is Dehydrated to 15d-PGA2
PGJ2 Is Isomerised to Delta12-PGJ2
PGH2 Diffuses From the Endoplasmic Reticulum Lumen to the Cytosol
ASA- Acetylates PTGS2
Cyclooxygenase Pathway
PTGS1 Dimer Binds PTGS1 Inhibitors
PGH2 Is Degraded to 12S-HHT and MDA by TBXAS1
PGE2 Is Converted to PGF2a by CBR1
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