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HS-GAG Degradation - Ontify

HS-GAG Degradation

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2024096).

Statements about HS-GAG Degradation

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Instance Of

Biological Pathway

Glycosaminoglycan Catabolic Process

Part Of

Heparan Sulfate/Heparin (HS-GAG) Metabolism

Has Part(s)

14 items

Exact Match

https://identifiers.org/reactome:R-H ...

SGSH Hydrolyses Heparan Sulfate Chain(2)

IDS Hydrolyses Heparan Sulfate Chain(5)

HS-GAGs Translocate to the Lysosome for Degradation

Heparanase (HPSE) Cleaves Heparan Sulfate From Its Proteoglycan (Lysosome)

GLB1 Hydrolyses Linker Chain(2)

HGSNAT Oligomer Acetylates Heparan Sulfate Chain(3)

NAGLU Hydrolyses Heparan Chain(2)

IDUA Hydrolyses Heparan Sulfate Chain(1)

NAGLU Hydrolyses Heparan Sulfate Chain(4)

SGSH Hydrolyses Heparan Sulfate Chain(7)

IDUA Hydrolyses Heparan Sulfate Chain(6)

Heparanase 2 (HPSE2) Cleaves Heparan Sulfate From Its Proteoglycan (Plasma Membrane)

HGSNAT Oligomer Acetylates Heparan Chain(1)

GUSB Tetramer Hydrolyses CS/HS Precursor