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HS-GAG Biosynthesis - Ontify
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HS-GAG Biosynthesis
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2022928).
Statements about
HS-GAG Biosynthesis
Instance Of
Biological Pathway
Heparan Sulfate Proteoglycan Biosynthetic Process
Part Of
Heparan Sulfate/Heparin (HS-GAG) Metabolism
Has Part(s)
14 items
SLC35D2 Exchanges UDP-Sugars for UMP
EXT1:EXT2 Transfers GlcNAc to the Terminal GlcA Residue
EXT1:EXT2 Transfers GlcNAc to Heparan
EXT1:EXT2 Transfer GlcNAc to the Heparan Chain
EXT1:EXT2 Transfers GlcA to Heparan
NDST1-4 N-Deacetylates GlcNAc Residues in Heparan
NDST1-4 Can Sulfate a Glucosamine Residue in Heparan to Form Heparan Sulfate (HS)
GLCE Epimerises GlcA to IdoA
HS2ST1 Sulfates IdoA at C2 in Heparan Sulfate
HS3STs Sulfate GlcN at C3 in Heparan Sulfate
HS3ST1 Sulfates GlcN at C3 in Heparan Sulfate
GLCE Epimerises More GlcA to IdoA as Sulfate Content Rises
HS6STs Sulfate GlcN at C6 in Heparan Sulfate/Heparin
Some HSPGs Are Secreted to the Plasma Membrane
Exact Match
https://identifiers.org/reactome:R-H ...
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