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Negative Regulation of MAPK Pathway
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5675221).
Statements about
Negative Regulation of MAPK Pathway
Instance Of
Biological Pathway
Has Part(s)
15 items
Negative Feedback Regulation of MAPK Pathway
PP2A Dephosphorylates RAF1
Cytosolic DUSPs Dephosphorylate MAPKs
Nuclear DUSPs Dephosphorylate MAPKs
BRAP Autoubiquitinates
PTPN7 Binds P-T,Y-MAPK
PTPN7 Dephosphorylates P-T,Y-MAPKs
PTPN3 Binds P-T183,Y185 MAPK12
Part Of
RAF/MAP Kinase Cascade
Exact Match
https://identifiers.org/reactome:R-H ...
PEBP1 Binds Activated RAF1
PTPN3 Dephosphorylates MAPK12
MAPK12 Phosphorylates PTPN3
PP5 Dephosphorylates RAF1 S338
BRAP Binds RAS:GTP
PAQR3 Binds Inactive RAFs
BRAP Binds KSR1:MARK3
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