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RAF Activation - Ontify
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RAF Activation
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5673000).
Statements about
RAF Activation
Instance Of
Biological Pathway
Part Of
RAF/MAP Kinase Cascade
Has Part(s)
12 items
Inactive RAFs Bind YWHAB
PP2A Dephosphorylates Inactive RAFs
YWHAB Dimer Dissociates From Dephosphorylated RAF
RAS:GTP:'activator' RAF Homo/Heterodimerizes with Other RAF Monomers
MARK3 Phosphorylates KSR1
P-S311,S406 KSR1:MARK3 Binds YWHAB Dimer
PP2A Dephosphorylates KSR1
YWHAB Dimer Dissociates From KSR1:MARK3
Exact Match
https://identifiers.org/reactome:R-H ...
"Activator" RAF:YWHAB Dimer Binds RAS:GTP
Phosphorylation of RAF
MRAS:SHOC2:PPP1CC Dephosphorylates Inactive RAFs
Raf Dimer Inhibitors Bind RAF Heterodimers
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