Ontify
⌘
S
⌘
S
Share
Interleukin-20 Family Signaling
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-8854691).
Statements about
Interleukin-20 Family Signaling
Instance Of
Biological Pathway
Cytokine-Mediated Signaling Pathway
Has Part(s)
56 items
P-Y705-STAT3 Dimerizes
IL20RA Binds IL20RB
IL19 Binds IL20RA:JAK1:IL20RB
IL20 Binds IL20RA:JAK1:IL20RB
IL24 Binds IL20RA:JAK1:IL20RB
IL24 Binds to IL22RA1:JAK1:IL20RB
IL22RA2 Binds IL22
IL22 Binds IL22RA1:JAK1 Receptor Complex
IL22:IL22RA1:JAK1 Binds IL10RB:TYK2
IFNL1 Binds IL10RB:TYK2 and IFNLR1:JAK1
P-Y705-STAT3 Dimer Translocates From Cytosol to Nucleoplasm
IL19:IL20RA:p‑JAK1:IL20RB Binds STAT3
JAK1 Binds IL20RA
IL19:IL20RA:JAK1:IL20RB Phosphorylates JAK1
P‑Y705-STAT3 Dissociates From IL19:IL20RA:p-JAK1:IL20RB
IL19:IL20RA:p-JAK1:IL20RB:STAT3 Phosphorylates STAT3
IL20:IL20RA:JAK1:IL20RB Binds JAK2,JAK3
IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 Binds STAT3
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 Phosphorylates JAK2,JAK3
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 Phosphorylates STAT3
P-STAT3 Dissociates From IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3
JAK1 in IL24:IL20RA:JAK1:IL20RB Is Phosphorylated
IL24:p-IL20RA:p-JAK1:IL20RB Binds STAT1,STAT3
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 Phosphorylates STAT1 or STAT3
P-STAT1,p-STAT3 Dissociate From IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, P-STAT3
P-STAT3 Dimerizes
P-STAT1 Dimerizes
P-STAT3 Dimer Translocates From Cytosol to Nucleoplasm
P-STAT1 Dimer Translocates From the Cytosol to the Nucleoplasm
Expression of SOCS3
IL20 Binds to IL22RA1:JAK1:IL20RB
IL24:IL22RA1:JAK1:IL20RB Phosphorylates JAK1
IL24:IL22RA1:p-JAK1:IL20RB Binds STAT3
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 Phosphorylates STAT3
P-STAT3 Dissociates From IL24:IL22RA1:p‑JAK1:IL20RB:p‑STAT3
IL26 Binds IL20RA:JAK1
IL10RB Binds TYK2
IL26:IL20RA:JAK1 Binds IL10RB:TYK2
IL26:IL20RA:JAK1:IL10RB:TYK2 Phosphorylates JAK1, TYK2
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 Binds STAT1, STAT3
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 Phosphorylates STAT1,STAT3
P-STAT1 and P-STAT3 Dissociates From IL26:IL10RB:p-TYK2:IL20RA:p-JAK1
IL22RA1 Binds JAK1
IL22:IL22RA1:JAK1:IL10RB:TYK2 Phosphorylates JAK1,TYK2
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 Phosphorylates IL22RA
IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 Binds PTPN11
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 Binds STAT3
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 Phosphorylates STAT3
P-Y705-STAT3 Dissociates From IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3
JAK1 Binds IFNLR1
IFNL2,IFNL3 Bind IL10RB:TYK2 and IFNLR1:JAK1
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 Phosphorylates JAK1,TYK2
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 Phosphorylates IFNLR1
IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 Binds STAT1, STAT2, STAT3, STAT4, STAT5
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 Phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5
P-STAT1, P-Y-STAT2, P-STAT3, P-STAT4, P-STAT5 Dissociates From IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5
Part Of
Signaling by Interleukins
Exact Match
https://identifiers.org/reactome:R-H ...
WikidataWikidataWikidata