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Interleukin-37 Signaling - Ontify
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Interleukin-37 Signaling
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9008059).
Statements about
Interleukin-37 Signaling
Instance Of
Biological Pathway
Cellular Response to Cytokine Stimulus
Part Of
Interleukin-1 Family Signaling
Has Part(s)
14 items
IL37 Binds IL18R1
IL37(?-218) Translocates From the Cytosol to the Nucleus
PTPNs Gene Transcription and Translation
IL37(?-218):p-S423,S425-SMAD3 Translocates to the Nucleus
IL37(?-218) Binds P-S423,S425-SMAD3
IL37 Binds 2x(CASP1(120-197):CASP1(317-404))
IL37:2x(CASP1(120-197):CASP1(317-404)) Cleaves IL37
IL37(1-?) and IL37 (?-) Dissocates From IL37(1-?):IL37(?-218):CASP1(120-197):CASP1(317-404)
IL37:IL18R1 Binds SIGIRR
IL37, IL37(?-218) Binds IL18BP
TBK1 Phosphorylation
IL37(?-218) Binds SMAD3
IL37, IL37(?-218) Translocates From Cytosol to Extracellular Region
STAT3 Phosphorylation
Exact Match
https://identifiers.org/reactome:R-H ...
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