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Regulation of Actin Dynamics for Phagocytic Cup Formation - Ontify
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Regulation of Actin Dynamics for Phagocytic Cup Formation
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2029482).
Statements about
Regulation of Actin Dynamics for Phagocytic Cup Formation
Instance Of
Biological Pathway
Part Of
Fcgamma Receptor (FCGR) Dependent Phagocytosis
Has Part(s)
24 items
Dimerization of LIMK1 by Hsp90
Transphosphorylation of pLIMK1
Phosphorylation of Cofilin by LIMK-1
Recruitment of VAV1 to P-6Y-SYK
Phosphorylation of VAV
Activation of RAC1 by VAV
Recruitment of CRKII:DOCK180:ELMO Complex to FCGR
Activation of RAC1 by CRKII:DOCK180:ELMO
RAC1:GTP and PIP3 Bind WAVE Regulatory Complex (WRC)
P-ERK Phosphorylates WAVEs and ABI
ABL Phosphorylates WAVEs
An Unknown GEF Exchanges GTP for GDP on CDC42:GDP
Activation of WASP and N-WASP by CDC42
WIP Binds WASP,N-WASP, Activating Them
Src Phosphorylate WASP,N-WASP
WASPs or WAVEs Activate the ARP2/3 Complex
(WASPs, WAVE):G-Actin:ARP2/3 Binds F-Actin
Detachment of WASP/WAVE
Branching and Elongation of Mother and Daughter Filaments
RAC1 and CDC42 Activate PAK1
Autophosphorylation of PAK1
PAK1 Phosphorylates LIMK1
Extension of Pseudopodia by Myosin-X in a PI3K Dependent Manner
Role of Myosins in Phagosome Formation
Exact Match
https://identifiers.org/reactome:R-H ...
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