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Regulation of Innate Immune Responses to Cytosolic DNA

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-3134975).

Statements about Regulation of Innate Immune Responses to Cytosolic DNA

Instance Of

Biological Pathway
Regulation of Type I Interferon Production

Has Part(s)

Regulation by TREX1
DDX41 Ubiquitination by TRIM21
STING Binds TRIM32 or TRIM56
STING Ubiquitination by TRIM32 or TRIM56
NLRP4 and DTX4 Associate with P-S172-TBK1 Within dsDNA:ZBP1:TBK1
NLRP4 and DTX4 Associate with P-S172-TBK1 Within STING:TBK1:IRF3
DTX4 Ubiquitinates P-S172-TBK1 Within NLRP4:DTX4:dsDNA:ZBP1:TBK1
DTX4 Ubiquitinates P-S172-TBK1 Within NLRP4:DTX4:STING:TBK1:IRF3

Part Of

Cytosolic Sensors of Pathogen-Associated DNA

Exact Match

https://identifiers.org/reactome:R-H ...
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