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Regulation of Complement Cascade - Ontify
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Regulation of Complement Cascade
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-977606).
Statements about
Regulation of Complement Cascade
Instance Of
Biological Pathway
Part Of
Complement Cascade
Has Part(s)
42 items
C3a Receptor Binds Anaphylatoxin C3a
C5a Receptor Binds C5a Anaphylatoxin
Clusterin Binds C5b-C7, C8, C9
C5AR2 Binds Anaphylatoxins and Thier desArginated Derivatives
Exact Match
https://identifiers.org/reactome:R-H ...
Factor H Binds to C3b
Complement Factor I Complex Formation
Factor H Binds to C3bBb
C1-Inh Binds and Inactivates C1r, C1s
Factor I Inactivates Plasma Factor H-Bound C3b
Factor H Binds Host Cell Surface Markers
CD46 Binds C3b
Factor H Displaces Bb
CFHR Dimers Bind C3b
CR2:C3d,C3dg,iC3b Binds CD19:CD81
CD59 Inhibits MAC Formation
Thrombin, ELANE Cleave C5
CD55 (DAF) Promotes C3bBb/C4bC2a Dissociation
C3 Convertases Spontaneously Dissociate
Complement Factor I Binds C4BP
Factor I Inactivates Factor H-boundC3b
Formation of Soluble VTN:C5b-C9
Complement Factor I Binds to MCP, CR1:C4b, C3b
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 Dissociates
Factor H Binds to Membrane-Associated C3b
CR2 Binds C3d, C3dg, iC3b
Displacement of C2a/Bb by CR1
Regulation of Complement Activation
CD55 (DAF) Binds C3bBb, C4bC2a
C4b Binding Protein Binds Protein S
C4b-Binding Protein Binds C4b
Vitronectin (VTN) Binds to C5b:C6:C7
Factor I Cleaves iC3b
C4b Binding Protein Displaces C2a
C1-Inh Binds Antigen: Antibody: C1 Complex Activated C1r, C1s
CR1 Binds C3bBb/C4bC2a
Hydrolysis of Internal Thioester in C4b
Complement Factor I Binds to Extracellular Factor H:C3b
Complement Factor I Binds to Membrane-Associated Factor H:C3b
C4b Binding Protein Binds C4bC2a
Complement Factor I Inactivates C4BP-Bound C4b
CPN, CPB2 Cleave C3a, C5a
CD46 Binds C4b
Factor I Inactivates MCP/CR1-Bound C4b/C3b
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