Ontify
⌘
S
⌘
S
Activation of NF-kappaB in B Cells - Ontify
Share
Activation of NF-kappaB in B Cells
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-1169091).
Statements about
Activation of NF-kappaB in B Cells
Instance Of
Biological Pathway
Part Of
Downstream Signaling Events of B Cell Receptor (BCR)
Has Part(s)
10 items
PRKCB (Protein Kinase C Beta, PKC-Beta) Binds Diacylglycerol and Phosphatidylserine
PRKCB (PKC-Beta) Phosphorylates CARMA1
CARMA1 Recruits MALT1 and BCL10 Forming CBM Complex
CARMA1:BCL10:MALT1 Complex Recruits TAK1 and IKK
TAK1 Associated with the CBM Complex Phosphorylates IKKbeta
Activated IKK Phosphorylates I-kappaB
SCF with Beta-TrCP1 or Beta-TrCP2 Binds NF-kappaB:phospho-IkB
SCF-Beta-TrCP Ubiquitinylates IkB
Ubiquitinated IkB Is Degraded
NF-kappaB Translocates From the Cytosol to the Nucleus
Exact Match
https://identifiers.org/reactome:R-H ...
WikidataWikidataWikidata