Ontify

⌘S

CD28 Dependent PI3K/Akt Signaling - Ontify

CD28 Dependent PI3K/Akt Signaling

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-389357).

Statements about CD28 Dependent PI3K/Akt Signaling

Powered by

Instance Of

Biological Pathway

Part Of

CD28 Co-Stimulation

Has Part(s)

PI3K Binds CD28

CD28 Bound PI3K Phosphorylates PIP2 to PIP3

PIP3 Recruits PDPK1 to the Membrane

PIP3 Recruits AKT to the Membrane

PDPK1 Phosphorylates AKT at T308

TORC2 (mTOR) Phosphorylates AKT at S473

AKT Binds PDPK1

AKT Interacts and Phosphorylates Cot

P-S400-Cot Phosphorylates NIK

Exact Match

https://identifiers.org/reactome:R-H ...