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Downstream TCR Signaling - Ontify
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Downstream TCR Signaling
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-202424).
Statements about
Downstream TCR Signaling
Instance Of
Biological Pathway
Part Of
TCR Signaling
Has Part(s)
24 items
PTEN Dephosphorylates PIP3
Translocation of PKC Theta to Plasma Membrane
Change of PKC Theta Conformation
Auto-Ubiquitination of TRAF6
Activation of IKK Complex
Ubiquitination of NEMO by TRAF6
P-S177,S181-IKKB:IKKA:pUb-NEMO Phosphorylates IkB-Alpha:NF-kB
26S Proteasome Processes K48PolyUb-K21,22-P-S32,36-IkBA:NF-kB Complex to Form NF-kB Complex
Beta-TRCP Ubiquitinates IkB-Alpha in P-S32,33-IkB-Alpha:NF-kB Complex
NFKB1:RELA Translocates From the Cytosol to the Nucleus
Exact Match
https://identifiers.org/reactome:R-H ...
Recruitment of PI3K to Plasma Membrane
Phosphorylation of PKC Theta
Phosphorylation of CARMA1
Oligomerization of CARMA1
Interaction of Bcl10 to CARMA1
Activation of TAK1-TAB2 Complex
Oligomerization of Bcl10
Translocation of TRAF6 to CBM Complex
Hydrolysis of PIP3 to PI(3,4)P2
Translocation of PDK1 to Plasma Membrane
PI3K Bound to TRAT1 Phosphorylates PIP2 to PIP3
Interaction and Oligomerization of MALT1 to Bcl10
Translocation of CARMA1 to Plasma Membrane
Phosphorylation of Bcl10
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