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Integrin Signaling - Ontify

Integrin Signaling

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-354192).

Statements about Integrin Signaling

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Instance Of

Biological Pathway

Has Part(s)

21 items

GRB2:SOS Provides Linkage to MAPK Signaling for Integrins

P130Cas Linkage to MAPK Signaling for Integrins

Activation of Rap1 by Cytosolic GEFs

Activation of Rap1 by Membrane-Associated GEFs

Translocation of RIAM to Plasma Membrane

Activation of Talin

Integrin alphaIIb Beta3 Activation

Interaction of Integrin alphaIIb Beta3 with Fibrinogen

Clustering of Integrin alphaIIb Beta3 Complexes

Release of CSK From SRC

Dephosphorylation of Inactive SRC by PTPB1

Autophosphorylation of SRC

Translocation of PTK2 to Focal Complexes

Autophosphorylation of PTK2 at Y397

Phosphorylation of pPTK2 by SRC

Integrin Alpha IIb Beta3 T779 Phosphorylation Blocks SHC Binding

Activated Integrin alphaIIb Beta3 Binds SHC1

SHC1 Bound to Integrin alphaIIb Beta3 Is Phosphorylated Somehow

SHC1 Dissociates From Integrin alphaIIb Beta3

SYK Binds to Integrin alphaIIb Beta3

SYK Activation by SRC

Part Of

Platelet Aggregation (Plug Formation)

Signal Transduction

Exact Match

https://identifiers.org/reactome:R-H ...