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Regulation of RUNX2 Expression and Activity - Ontify
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Regulation of RUNX2 Expression and Activity
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-8939902).
Statements about
Regulation of RUNX2 Expression and Activity
Instance Of
Biological Pathway
Part Of
Transcriptional Regulation by RUNX2
Has Part(s)
32 items
Activated ESR1 Binds the RUNX2 Gene Promoter
ESRRA:PPARG1CA Binds the RUNX2 Gene Promoter
ESRRA:PPARG1CB Binds the RUNX2 Gene Promoter
TWIST1 Binds the RUNX2 Gene Promoter
RUNX2 Gene Expression From Proximal (P2) Promoter Is Stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and Inhibited by ESRRA:PPARG1CB and DEXA:NR3C1
NKX3-2 Binds RUNX2 Gene Promoter
DEXA:NR3C1 Complex Binds RUNX2 Gene Proximal Promoter
RUNX2-P2 Binds RUNX2 Gene Promoter
RUNX2-P1 Binds RUNX2 Gene Promoter
RUNX2 Gene Expression From Distal (P1) Promoter Is Inhibited by NKX3-2, MSX2 and RUNX2-P1, and Stimulated by DLX5,(DLX6)
DLX5,(DLX6) Binds RUNX2 Gene Promoter
MSX2 Binds RUNX2 Gene Promoter
RUNX2 Binds STAT1
RUNX2 Translocates to the Nucleus
RUNX2 Binds to HIVEP3 and WWP1
WWP1 Polyubiquitinates RUNX2
Proteasome Degrades Polyubiquitinated RUNX2
RUNX2 Binds GSK3B
GSK3B Phosphorylates RUNX2
FBXW7 Binds RUNX2 and GSK3B
FBXW7 Polyubiquitinates RUNX2
RUNX2 Binds STUB1
STUB1 Polyubiquitinates RUNX2
RUNX2 Binds SMURF1 Gene
Proteasome Degrades PolyUb-RUNX2
RUNX2 Binds SMURF1
SMURF1 Polyubiquitinates RUNX2
SMURF1 Gene Expression Is Stimulated by RUNX2
SCF(SKP2) Complex Binds RUNX2
SCF(SKP2) Polyubiquitinates RUNX2
26S Proteasome Degrades PolyUb-RUNX2
Proteasome Degrades Polyubiquitinated RUNX2
Exact Match
https://identifiers.org/reactome:R-H ...
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