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RUNX1 Regulates Genes Involved in Megakaryocyte Differentiation and Platelet Function - Ontify

RUNX1 Regulates Genes Involved in Megakaryocyte Differentiation and Platelet Function

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-8936459).

Statements about RUNX1 Regulates Genes Involved in Megakaryocyte Differentiation and Platelet Function

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Instance Of

Biological Pathway

Regulation of Megakaryocyte Differentiation

Part Of

Transcriptional Regulation by RUNX1

Has Part(s)

33 items

RUNX1 Binds PRMT1

PRMT1 Arginine-Methylates RUNX1

RUNX1 Binds SIN3A,(SIN3B) Co-Repressor

RUNX1 and GATA1 Bind the Promoter of the ITGA2B Gene

Core MLL Complex Methylates H3K4Me2-Nucleosome at the ITGA2B Gene Promoter

RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 Bind the ITGA2B Promoter

ITGA2B Gene Transcription Is Stimulated by the Complex of RUNX1, GATA1 and PRMT1 and Inhibited by the Complex of RUNX1, SIN3A and PRMT6

PRMT6 Arginine Methylates H3K4me2-Nucleosome at the ITGA2B Gene Promoter

RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 Bind the GP1BA Promoter

PRMT6 Arginine Methylates H3K4me2-Nucleosome at the GP1BA Gene Promoter

RUNX1 and GATA1 Bind the Promoter of the GP1BA Gene

Core MLL Complex Methylates H3K4Me2-Nucleosome at the GP1BA Gene Promoter

GP1BA Gene Transcription Is Stimulated by the Complex Containing RUNX1, PRMT1 and GATA1 and Inhibited by the Complex of RUNX1, SIN3A and PRMT6

RUNX1 and GATA1 Bind the Promoter of the THBS1 Gene

Core MLL Complex Methylates H3K4Me2-Nucleosome at the THBS1 Gene Promoter

RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 Bind the THBS1 Gene Promoter

PRMT6 Arginine Methylates H3K4me2-Nucleosome at the THBS1 Gene Promoter

THBS1 Gene Transcription Is Stimulated by the Complex Containing RUNX1, PRMT1 and GATA1 and Inhibited by the Complex of RUNX1, SIN3A and PRMT6

RUNX1 and GATA1 Bind the Promoter of the MIR27A Gene

Core MLL Complex Methylates H3K4Me2-Nucleosome at the MIR27A Gene Promoter

RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 Bind the MIR27A Gene Promoter

PRMT6 Arginine Methylates H3K4me2-Nucleosome at the MIR27A Gene Promoter

MIR27A Gene Transcription Is Stimulated by the Complex Containing RUNX1, PRMT1 and GATA1 and Inhibited by the Complex of RUNX1, SIN3A and PRMT6

RUNX1:CBFB Binds the NR4A3 Gene Promoter

PF4 Gene Transcription Is Stimulated by RUNX1:CBFB

RUNX1:CBFB Binds the PF4 Gene Promoter

NR4A3 Gene Expression Is Stimulated by RUNX1:CBFB

RUNX1:CBFB Binds the PRKCQ Gene Promoter

PRKCQ Gene Expression Is Stimulated by RUNX1:CBFB

RUNX1:CBFB Binds the MYL9 Gene Promoter

MYL9 Gene Transcription Is Stimulated by RUNX1:CBFB

RUNX1:CBFB Binds the NFE2 Gene Promoter

NFE2 Gene Expression Is Stimulated by RUNX1:CBFB

Exact Match

https://identifiers.org/reactome:R-H ...