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Uptake and Function of Anthrax Toxins - Ontify

Uptake and Function of Anthrax Toxins

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5210891).

Statements about Uptake and Function of Anthrax Toxins

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Instance Of

Biological Pathway

Part Of

Uptake and Actions of Bacterial Toxins

Has Part(s)

20 items

PagA Binds ANTXR1

PagA Binds ANTXR2

Furin Cleaves ANTXR1-Bound pagA to Yield pagA(197-794)

Furin Cleaves ANTXR2-Bound pagA to Yield pagA(197-794)

ANTXR1-Bound pagA(197-794) Forms Oligomers

ANTXR2-Bound pagA(197-794) Forms Oligomers

Cya and Lef Bind to pagA(197-794):ANTXR1 Oligomer

Cya and Lef Bind to pagA(197-794):ANTXR2 Oligomer

Endocytosis of Cya:lef:(pagA(197-794):ANTXR1 Oligomer) (Plasma Membrane to Endosome Membrane)

PagA(197-794):ANTRX1 Oligomer Transports Cya and Lef (Target Cell Endosome to Cytosol)

Endocytosis of Cya:lef:(pagA(197-794):ANTXR2 Oligomer) (Plasma Membrane to Endosome Membrane)

PagA(197-794):ANTRX2 Oligomer Transports Cya and Lef (Target Cell Endosome to Cytosol)

Anthrax Cya Catalyzes the Conversion of ATP to cAMP

Anthrax Lef Cleaves Target Cell MAP2K1 (MEK1)

Anthrax Lef Cleaves Target Cell MAP2K2 (MEK2)

Anthrax Lef Cleaves Target Cell MAP2K3 (MEK3)

Anthrax Lef Cleaves Target Cell MAP2K4 (MEK4)

Anthrax Lef Cleaves Target Cell MAP2K6 (MEK6)

Anthrax Lef Cleaves Target Cell MAP2K7 (MEK7)

FURIN Binds Furin Inhibitors

Exact Match

https://identifiers.org/reactome:R-H ...